According to Nutrigenomics, or the science that studies the interaction between food and human genes, a person’s genetic makeup decides how foods are utilized in his body. Food manufacturers invest in nutrigenomics and devise new products that cater to specific people with specific genetic makeup. Nutritionists are able to calculate nutritional supplements and create personalized nutrition plan based on a certain person’s genetic constitution.

Also, pharmaceutical companies are able to formulate customized vitamins and supplements specifically for a certain group of individuals as based on how their genes react to such nutrients to achieve optimum level of good health, and to fight chronic diseases.

Each person is affected by nutrigenomics as everyone needs food to live, and every human body has genetic materials. According to health experts, the diseases commonly found in most Westerners such as diabetes, metabolic syndrome, heart disease, arthritis, and obesity have strong associations between their genes and the foods they consume.

These health professionals suggest that by increasing consumption on whole foods derived from plants-like fruits and vegetables, nuts, herbs, seeds, and whole grains-and decreasing on red meat-which means more fish-and processed foods, people can mitigate the onslaught of genetically induced diseases.
One good example is the increasing evidence that antioxidants like vitamin E, C, carotenoids such as beta-carotene, lutein, zeaxanthin, and flavanoids like hesperition, quercetin, and caffeic acid impact gene expression.

The antioxidants can block gene expression to inhibit adverse metabolic pathways. Kamagra An evidence to this is how flavanoids down-regulate Nuclear Factor-Kappa B or NF-Kappa B. NF-Kappa B is a transcription factor regulating genes involved in immune responses, inflammatory, apoptosis and tumor production. Chronic inflammation has been closely associated with diabetes, metabolic syndrome, atherosclerosis, heart disease, arthritis and obesity.

NF-Kappa B regulate a few genes involved in developing atherosclerosis including genes encoding for cytokines, cell adhesion such as monocyte chemotactic protein or MCP-1, and chemoattractants. MCP-1 is also linked with insulin resistance, obesity and fatty liver. Cytokines, on the other hand, are proteins discharged by the human immune system cells, and which act as messengers to regulate an immune response.

As of today, there are more than 25,000 biologically active food components, and health researchers have only discovered the mode of action of several compounds. Regardless of this, government health agencies, primary health care providers, and health professionals emphasize the need for living a healthy lifestyle, which composes of physical exercise and nutritious diet.

Some diet-related genes play a key role in the beginning, incidence, progression and severity of chronic diseases. Dietary interference based on nutritional needs and genotype can be a powerful tool to prevent, reduce or cure chronic diseases.

A diet that is nutritious contains more leafy vegetables, fruits, healthy fats-such as un-hydrogenated vegetable oils, virgin olive oil, walnut oil, avocado oil-whole grains, lean meats, fish, lower-fat dairy and dairy products.
Avoiding smoking or drinking too much alcoholic beverages should also be a part of one’s daily regimen, together with sufficient rest and sleep, and taking steps to relieve stress.

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