Background Many new drug molecules have solubility problems with some having almost no aqueous solubility. This creates formulation development issues since many standard formulation techniques may not be successful in delivering a drug orally. A common approach to improving oral delivery is to use the amorphous form of an active pharmaceutical ingredient. The amorphous form […]
It’s hard to avoid CROs these days. From two-person virtual companies to the largest multinationals, everyone is outsourcing, and like everything else, this trend has its pluses and minuses. For those new to the game, we thought we would address some perceptions and realities we have found in working with pharmaceutical CROs. Perception: Once you […]
It is sometimes amazing what people do to get insoluble drugs into laboratory animals. While a slightly crazy formulation may be the best option for early animal studies, if you get married to it, the divorce could get messy. We formulators like to gripe about not getting enough attention. In a previous newsletter article we […]
There are a lot of products that you may use in order to see to it that you will be able to maintain a young-looking and glowing skin. However, why would you waste your money in buying these substances when everything that you need in order to achieve glowing skin is right inside your home? […]
Ear, Nose, and Throat doctors (or ENTs) perform just under 5% of all surgeries in the US each year – that translates to more than 3.5 million procedures a year. These types of interventions can be lifesavers for patients, some of whom may struggle with painful conditions until they receive surgery. Interestingly, pain management for […]
In order to avoid pimples and acne, it is advisable to understand the causes of the pimples and acne formation. Almost everyone often repeatedly suffered from pimples and acne. It appears from time to time even at senior age due to strong endocrine or disorder making pimples and acne relatively troublesome. Many people quest for […]
Neck pain can arise due to a variety of causes, including overuse of the muscles, nerve compression, and even diseases like rheumatoid arthritis. Because it can result from such a range of sources, there are several tests that can be used to find the underlying condition. Depending on the symptoms you present, your doctor may […]
Probably the most common kind of vision problem that people have these days is myopia, commonly known as nearsightedness. For nearsighted people, they can only see things clearly when they are up close, but when the object is at a distance, they will need glasses to see them clearly. The lens in the eyes of […]
Hemorrhoids, also called “Piles”, are basically inflamed blood vessels or tissues inside the anus or the rectum. Thousands or even millions of people suffer from this condition. The market offers plenty of hemorrhoid treatment available in order to ease the hot, uncomfortable and itchy feeling that hemorrhoids cause. But the treatments won’t cure it, it […]
When men believe to be \”finished\” about having children, they undergo vasectomy, which is a surgical procedure that prevents the sperm from entering the semen. After a while, many of these men change their minds about their decision on not having children again. Once they have decided to have more children, they go to a […]
